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Population Bottlenecks Strongly Influence the Evolutionary Trajectory to Fluoroquinolone Resistance in Escherichia coli
Experimental evolution is a powerful tool to study genetic trajectories to antibiotic resistance under selection. A confounding factor is that outcomes may be heavily influenced by the choice of experimental parameters. For practical purposes (minimizing culture volumes), most experimental evolution...
Autores principales: | Garoff, Linnéa, Pietsch, Franziska, Huseby, Douglas L, Lilja, Tua, Brandis, Gerrit, Hughes, Diarmaid |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7253196/ https://www.ncbi.nlm.nih.gov/pubmed/32031639 http://dx.doi.org/10.1093/molbev/msaa032 |
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