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Therapeutic Reversal of Radiotherapy Injury to Pro-fibrotic Dysfunctional Fibroblasts In Vitro Using Adipose-derived Stem Cells

Cancer patients often require radiotherapy (RTx) to enhance their survival. Unfortunately, RTx also damages nearby healthy non-cancer tissues, leading to progressive fibrotic soft-tissue injury, consisting of pain, contracture, tissue-breakdown, infection, and lymphoedema. Mechanisms underlying the...

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Detalles Bibliográficos
Autores principales: Shukla, Lipi, Luwor, Rodney, Ritchie, Matthew E., Akbarzadeh, Shiva, Zhu, Hong-Jian, Morrison, Wayne, Karnezis, Tara, Shayan, Ramin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7253248/
https://www.ncbi.nlm.nih.gov/pubmed/32537359
http://dx.doi.org/10.1097/GOX.0000000000002706