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Entry and exit of chemotherapeutically-promoted cellular dormancy in glioblastoma cells is differentially affected by the chemokines CXCL12, CXCL16, and CX3CL1

Glioblastoma multiforme (GBM) is a malignant brain tumor that evades therapy regimens. Since cellular dormancy is one strategy for surviving, and since chemokines determine the environmental conditions in which dormancy occurs, we investigated how chemokines affect temozolomide (TMZ)-promoted cellul...

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Detalles Bibliográficos
Autores principales: Adamski, Vivian, Hattermann, Kirsten, Kubelt, Carolin, Cohrs, Gesa, Lucius, Ralph, Synowitz, Michael, Sebens, Susanne, Held-Feindt, Janka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7253351/
https://www.ncbi.nlm.nih.gov/pubmed/32346064
http://dx.doi.org/10.1038/s41388-020-1302-8