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Splicing factor proline- and glutamine-rich (SFPQ) protein regulates platinum response in ovarian cancer-modulating SRSF2 activity

In epithelial ovarian cancer (EOC), response to platinum (PT)-based chemotherapy dictates subsequent treatments and predicts patients’ prognosis. Alternative splicing is often deregulated in human cancers and can be altered by chemotherapy. Whether and how changes in alternative splicing regulation...

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Detalles Bibliográficos
Autores principales: Pellarin, Ilenia, Dall’Acqua, Alessandra, Gambelli, Alice, Pellizzari, Ilenia, D’Andrea, Sara, Sonego, Maura, Lorenzon, Ilaria, Schiappacassi, Monica, Belletti, Barbara, Baldassarre, Gustavo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7253352/
https://www.ncbi.nlm.nih.gov/pubmed/32332923
http://dx.doi.org/10.1038/s41388-020-1292-6