Cargando…
Splicing factor proline- and glutamine-rich (SFPQ) protein regulates platinum response in ovarian cancer-modulating SRSF2 activity
In epithelial ovarian cancer (EOC), response to platinum (PT)-based chemotherapy dictates subsequent treatments and predicts patients’ prognosis. Alternative splicing is often deregulated in human cancers and can be altered by chemotherapy. Whether and how changes in alternative splicing regulation...
Autores principales: | Pellarin, Ilenia, Dall’Acqua, Alessandra, Gambelli, Alice, Pellizzari, Ilenia, D’Andrea, Sara, Sonego, Maura, Lorenzon, Ilaria, Schiappacassi, Monica, Belletti, Barbara, Baldassarre, Gustavo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7253352/ https://www.ncbi.nlm.nih.gov/pubmed/32332923 http://dx.doi.org/10.1038/s41388-020-1292-6 |
Ejemplares similares
-
Identification and Characterization of a New Platinum-Induced TP53 Mutation in MDAH Ovarian Cancer Cells
por: Lorenzon, Ilaria, et al.
Publicado: (2019) -
Common biological phenotypes characterize the acquisition of platinum-resistance in epithelial ovarian cancer cells
por: Sonego, Maura, et al.
Publicado: (2017) -
Serum- and glucocorticoid- inducible kinase 2, SGK2, is a novel autophagy regulator and modulates platinum drugs response in cancer cells
por: Ranzuglia, Valentina, et al.
Publicado: (2020) -
CDK6 protects epithelial ovarian cancer from platinum‐induced death via FOXO3 regulation
por: Dall'Acqua, Alessandra, et al.
Publicado: (2017) -
USP1 links platinum resistance to cancer cell dissemination by regulating Snail stability
por: Sonego, Maura, et al.
Publicado: (2019)