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Polymorphic α-Synuclein Strains Modified by Dopamine and Docosahexaenoic Acid Interact Differentially with Tau Protein

The pathological hallmark of synucleinopathies, including Parkinson’s disease (PD), is the aggregation of α-synuclein (α-Syn) protein. Even so, tau protein pathology is abundantly found in these diseases. Both α-Syn and tau can exist as polymorphic aggregates, a phenomenon that has been widely studi...

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Detalles Bibliográficos
Autores principales: Sengupta, Urmi, Puangmalai, Nicha, Bhatt, Nemil, Garcia, Stephanie, Zhao, Yingxin, Kayed, Rakez
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7253398/
https://www.ncbi.nlm.nih.gov/pubmed/32350746
http://dx.doi.org/10.1007/s12035-020-01913-6