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Polymorphic α-Synuclein Strains Modified by Dopamine and Docosahexaenoic Acid Interact Differentially with Tau Protein
The pathological hallmark of synucleinopathies, including Parkinson’s disease (PD), is the aggregation of α-synuclein (α-Syn) protein. Even so, tau protein pathology is abundantly found in these diseases. Both α-Syn and tau can exist as polymorphic aggregates, a phenomenon that has been widely studi...
Autores principales: | Sengupta, Urmi, Puangmalai, Nicha, Bhatt, Nemil, Garcia, Stephanie, Zhao, Yingxin, Kayed, Rakez |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7253398/ https://www.ncbi.nlm.nih.gov/pubmed/32350746 http://dx.doi.org/10.1007/s12035-020-01913-6 |
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