The multidrug resistance can be reversed for the decrease of P-gp and LRP by inhibiting PI3K/Akt/NF-κB signal pathway in nasopharynx carcinoma

Aim: To investigate the relationship between PI3K/Akt/NF-κB cellular signal pathway and the expression of P-gp and LRP in multidrug resistance (MDR) cell of nasopharyngeal carcinoma. Method: The PI3K, p-Akt and NF-κB/p65 as the activity of PI3K/Akt/NF-κB were detected by Western blot. The expression...

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Detalles Bibliográficos
Autores principales: Liu, Jin, Zhu, Mingyi, Feng, Yun, Tang, Qianli, Xu, Meng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Cancer
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7253406/
https://www.ncbi.nlm.nih.gov/pubmed/32400857
http://dx.doi.org/10.1042/BSR20190239

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7253406/
https://www.ncbi.nlm.nih.gov/pubmed/32400857
http://dx.doi.org/10.1042/BSR20190239

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