Pregnancy reprograms the epigenome of mammary epithelial cells and blocks the development of premalignant lesions

Pregnancy causes a series of cellular and molecular changes in mammary epithelial cells (MECs) of female adults. In addition, pregnancy can also modify the predisposition of rodent and human MECs to initiate oncogenesis. Here, we investigate how pregnancy reprograms enhancer chromatin in the mammary...

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Detalles Bibliográficos
Autores principales: Feigman, Mary J., Moss, Matthew A., Chen, Chen, Cyrill, Samantha L., Ciccone, Michael F., Trousdell, Marygrace C., Yang, Shih-Ting, Frey, Wesley D., Wilkinson, John E., dos Santos, Camila O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7253414/
https://www.ncbi.nlm.nih.gov/pubmed/32461571
http://dx.doi.org/10.1038/s41467-020-16479-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7253414/
https://www.ncbi.nlm.nih.gov/pubmed/32461571
http://dx.doi.org/10.1038/s41467-020-16479-z

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