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Vulnerabilities in coronavirus glycan shields despite extensive glycosylation

Severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS) coronaviruses (CoVs) are zoonotic pathogens with high fatality rates and pandemic potential. Vaccine development focuses on the principal target of the neutralizing humoral immune response, the spike (S) glycoprotei...

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Detalles Bibliográficos
Autores principales: Watanabe, Yasunori, Berndsen, Zachary T., Raghwani, Jayna, Seabright, Gemma E., Allen, Joel D., Pybus, Oliver G., McLellan, Jason S., Wilson, Ian A., Bowden, Thomas A., Ward, Andrew B., Crispin, Max
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7253482/
https://www.ncbi.nlm.nih.gov/pubmed/32461612
http://dx.doi.org/10.1038/s41467-020-16567-0