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Kallistatin Attenuates Experimental Autoimmune Uveitis by Inhibiting Activation of T Cells

Experimental autoimmune uveoretinitis (EAU) is a mouse model of human autoimmune uveitis. EAU spontaneously resolves and is marked by ocular autoantigen-specific regulatory immunity in the spleen. Kallikrein binding protein (KBP) or kallistatin is a serine proteinase inhibitor that inhibits angiogen...

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Detalles Bibliográficos
Autores principales: Muhammad, Fauziyya, Avalos, Priscilla N., Mursalin, M. H., Ma, Jian-Xing, Callegan, Michelle C., Lee, Darren J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7253575/
https://www.ncbi.nlm.nih.gov/pubmed/32508841
http://dx.doi.org/10.3389/fimmu.2020.00975