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Dual Transcriptomic and Molecular Machine Learning Predicts all Major Clinical Forms of Drug Cardiotoxicity

Computational methods can increase productivity of drug discovery pipelines, through overcoming challenges such as cardiotoxicity identification. We demonstrate prediction and preservation of cardiotoxic relationships for six drug-induced cardiotoxicity types using a machine learning approach on a l...

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Detalles Bibliográficos
Autores principales: Mamoshina, Polina, Bueno-Orovio, Alfonso, Rodriguez, Blanca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7253645/
https://www.ncbi.nlm.nih.gov/pubmed/32508633
http://dx.doi.org/10.3389/fphar.2020.00639