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Inhibition of Catechol-O-methyltransferase Does Not Alter Effort-Related Choice Behavior in a Fixed Ratio/Concurrent Chow Task in Male Mice

Effort-related choice (ERC) tasks allow animals to choose between high-value reinforcers that require high effort to obtain and low-value/low-effort reinforcers. Dopaminergic neuromodulation regulates ERC behavior. The enzyme catechol-O-methyltransferase (COMT) metabolizes synaptically-released dopa...

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Detalles Bibliográficos
Autores principales: DeBrosse, Adrienne C., Wheeler, Abigail M., Barrow, James C., Carr, Gregory V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7253649/
https://www.ncbi.nlm.nih.gov/pubmed/32508604
http://dx.doi.org/10.3389/fnbeh.2020.00073