Quantification of mitochondrial DNA damage and copy number in circulating blood of patients with systemic sclerosis by a qPCR-based assay()()

BACKGROUND: Although not fully understood, oxidative stress has been implicated in the pathogenesis of different autoimmune diseases such as systemic sclerosis. Accumulating evidence indicates that oxidative stress can induce mitochondrial DNA (mtDNA) damage and variations in mtDNA copy number (mtDN...

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Detalles Bibliográficos
Autores principales: Movassaghi, Shafieh, Jafari, Sara, Falahati, Kowsar, Ataei, Mitra, Sanati, Mohammad Hossein, Jadali, Zohreh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Dermatologia 2020
Materias:
Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7253925/
https://www.ncbi.nlm.nih.gov/pubmed/32307203
http://dx.doi.org/10.1016/j.abd.2019.11.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7253925/
https://www.ncbi.nlm.nih.gov/pubmed/32307203
http://dx.doi.org/10.1016/j.abd.2019.11.003

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