Interaction of the prototypical α-ketoamide inhibitor with the SARS-CoV-2 main protease active site in silico: Molecular dynamic simulations highlight the stability of the ligand-protein complex

The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) causes an illness known as COVID-19, which has been declared a global pandemic with over 2 million confirmed cases and 137,000 deaths in 185 countries and regions at the time of writing (16 April 2020), over a quarter of these cases be...

Descripción completa

Detalles Bibliográficos
Autores principales: Liang, Julia, Pitsillou, Eleni, Karagiannis, Chris, Darmawan, Kevion K, Ng, Ken, Hung, Andrew, Karagiannis, Tom C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7253975/
https://www.ncbi.nlm.nih.gov/pubmed/32485652
http://dx.doi.org/10.1016/j.compbiolchem.2020.107292

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7253975/
https://www.ncbi.nlm.nih.gov/pubmed/32485652
http://dx.doi.org/10.1016/j.compbiolchem.2020.107292

Ejemplares similares