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Interaction of the prototypical α-ketoamide inhibitor with the SARS-CoV-2 main protease active site in silico: Molecular dynamic simulations highlight the stability of the ligand-protein complex

The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) causes an illness known as COVID-19, which has been declared a global pandemic with over 2 million confirmed cases and 137,000 deaths in 185 countries and regions at the time of writing (16 April 2020), over a quarter of these cases be...

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Detalles Bibliográficos
Autores principales:	Liang, Julia, Pitsillou, Eleni, Karagiannis, Chris, Darmawan, Kevion K, Ng, Ken, Hung, Andrew, Karagiannis, Tom C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Ltd. 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7253975/ https://www.ncbi.nlm.nih.gov/pubmed/32485652 http://dx.doi.org/10.1016/j.compbiolchem.2020.107292

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