The Identification of Potential Therapeutic Targets for Cutaneous Squamous Cell Carcinoma

We performed a small interfering RNA screen to identify targets for cutaneous squamous cell carcinoma (cSCC) therapy in the ubiquitin/ubiquitin-like system. We provide evidence for selective anti-cSCC activity of knockdown of the E3 ubiquitin ligase MARCH4, the ATPase p97/VCP, the deubiquitinating e...

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Detalles Bibliográficos
Autores principales: McHugh, Angela, Fernandes, Kenneth, Chinner, Nerime, Ibrahim, Adel F.M., Garg, Amit K., Boag, Garry, Hepburn, Lydia A., Proby, Charlotte M., Leigh, Irene M., Saville, Mark K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7254059/
https://www.ncbi.nlm.nih.gov/pubmed/31705877
http://dx.doi.org/10.1016/j.jid.2019.09.024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7254059/
https://www.ncbi.nlm.nih.gov/pubmed/31705877
http://dx.doi.org/10.1016/j.jid.2019.09.024

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