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The Identification of Potential Therapeutic Targets for Cutaneous Squamous Cell Carcinoma
We performed a small interfering RNA screen to identify targets for cutaneous squamous cell carcinoma (cSCC) therapy in the ubiquitin/ubiquitin-like system. We provide evidence for selective anti-cSCC activity of knockdown of the E3 ubiquitin ligase MARCH4, the ATPase p97/VCP, the deubiquitinating e...
Autores principales: | McHugh, Angela, Fernandes, Kenneth, Chinner, Nerime, Ibrahim, Adel F.M., Garg, Amit K., Boag, Garry, Hepburn, Lydia A., Proby, Charlotte M., Leigh, Irene M., Saville, Mark K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7254059/ https://www.ncbi.nlm.nih.gov/pubmed/31705877 http://dx.doi.org/10.1016/j.jid.2019.09.024 |
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