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FNDC5 Attenuates Oxidative Stress and NLRP3 Inflammasome Activation in Vascular Smooth Muscle Cells via Activating the AMPK-SIRT1 Signal Pathway

Vascular oxidative stress and inflammation play a major role in vascular diseases. This study was aimed at determining the protective roles of fibronectin type III domain-containing 5 (FNDC5) in angiotensin II- (Ang II-) induced vascular oxidative stress and inflammation and underlying mechanisms. W...

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Detalles Bibliográficos
Autores principales: Zhou, Bing, Qiu, Yun, Wu, Nan, Chen, Ai-Dong, Zhou, Hong, Chen, Qi, Kang, Yu-Ming, Li, Yue-Hua, Zhu, Guo-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7254086/
https://www.ncbi.nlm.nih.gov/pubmed/32509148
http://dx.doi.org/10.1155/2020/6384803