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Granzyme B PET imaging of immune-mediated tumor killing as a tool for understanding immunotherapy response

BACKGROUND: Cancer immunotherapy research is expanding to include a more robust understanding of the mechanisms of treatment response and resistance. Identification of drivers of pro-tumor and anti-tumor immunity during treatment offers new strategies for effective alternative or combination immunot...

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Detalles Bibliográficos
Autores principales: LaSalle, Thomas, Austin, Emily E, Rigney, Grant, Wehrenberg-Klee, Eric, Nesti, Sarah, Larimer, Benjamin, Mahmood, Umar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7254099/
https://www.ncbi.nlm.nih.gov/pubmed/32461343
http://dx.doi.org/10.1136/jitc-2019-000291