Inhibition of Activin/Myostatin signalling induces skeletal muscle hypertrophy but impairs mouse testicular development

Numerous approaches are being developed to promote post-natal muscle growth based on attenuating Myostatin/Activin signalling for clinical uses such as the treatment neuromuscular diseases, cancer cachexia and sarcopenia. However there have been concerns about the effects of inhibiting Activin on ti...

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Detalles Bibliográficos
Autores principales: Vaughan, Danielle, Ritvos, Olli, Mitchell, Robert, Kretz, Oliver, Lalowski, Maciej, Amthor, Helge, Chambers, David, Matsakas, Antonios, Pasternack, Arja, Collins-Hooper, Henry, Ballesteros, Randy, Huber, Tobias B., Denecke, Bernd, Widera, Darius, Mukherjee, Abir, Patel, Ketan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications, Pavia, Italy 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7254437/
https://www.ncbi.nlm.nih.gov/pubmed/32499882
http://dx.doi.org/10.4081/ejtm.2019.8737

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7254437/
https://www.ncbi.nlm.nih.gov/pubmed/32499882
http://dx.doi.org/10.4081/ejtm.2019.8737

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