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Inhibition of Activin/Myostatin signalling induces skeletal muscle hypertrophy but impairs mouse testicular development

Numerous approaches are being developed to promote post-natal muscle growth based on attenuating Myostatin/Activin signalling for clinical uses such as the treatment neuromuscular diseases, cancer cachexia and sarcopenia. However there have been concerns about the effects of inhibiting Activin on ti...

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Detalles Bibliográficos
Autores principales:	Vaughan, Danielle, Ritvos, Olli, Mitchell, Robert, Kretz, Oliver, Lalowski, Maciej, Amthor, Helge, Chambers, David, Matsakas, Antonios, Pasternack, Arja, Collins-Hooper, Henry, Ballesteros, Randy, Huber, Tobias B., Denecke, Bernd, Widera, Darius, Mukherjee, Abir, Patel, Ketan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	PAGEPress Publications, Pavia, Italy 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7254437/ https://www.ncbi.nlm.nih.gov/pubmed/32499882 http://dx.doi.org/10.4081/ejtm.2019.8737

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