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Design of Dual Inhibitors of Histone Deacetylase 6 and Heat Shock Protein 90

[Image: see text] Histone deacetylase 6 (HDAC6) and heat shock protein 90 (Hsp90) are widely investigated anticancer drug targets. Importantly, several lines of evidence indicate that their regulation and activity are intimately linked, and that their combined inhibition may lead to impressive thera...

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Detalles Bibliográficos
Autores principales: Pinzi, Luca, Benedetti, Rosaria, Altucci, Lucia, Rastelli, Giulio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7254527/
https://www.ncbi.nlm.nih.gov/pubmed/32478236
http://dx.doi.org/10.1021/acsomega.0c00559