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Polygenic risk scores for coronary artery disease and subsequent event risk amongst established cases

BACKGROUND: There is growing evidence that polygenic risk scores (PRSs) can identify individuals with elevated lifetime risk of coronary artery disease (CAD). Whether they can also be used to stratify the risk of subsequent events among those surviving a first CAD event remain uncertain, with possib...

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Detalles Bibliográficos
Autores principales: Howe, Laurence J, Dudbridge, Frank, Schmidt, Amand F, Finan, Chris, Denaxas, Spiros, Asselbergs, Folkert W, Hingorani, Aroon D, Patel, Riyaz S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7254844/
https://www.ncbi.nlm.nih.gov/pubmed/32219344
http://dx.doi.org/10.1093/hmg/ddaa052