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MiR-423-5p Regulates Cells Apoptosis and Extracellular Matrix Degradation via Nucleotide-Binding, Leucine-Rich Repeat Containing X1 (NLRX1) in Interleukin 1 beta (IL-1β)-Induced Human Nucleus Pulposus Cells

BACKGROUND: Disc degeneration is characterized partly by the degradation in the extracellular matrix (ECM) and excess apoptosis of nucleus pulposus (NP) cells. NLRX1 (nucleotide-binding, leucine-rich repeat containing X1) is different from the other nucleotide-binding-domain and leucine-rich-repeat...

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Detalles Bibliográficos
Autores principales: Xu, Hanrong, Ji, Liefeng, Yu, Chunhua, Chen, Qiming, Ge, Qiangqiang, Lu, Yinjiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7254941/
https://www.ncbi.nlm.nih.gov/pubmed/32467560
http://dx.doi.org/10.12659/MSM.922497