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Non-canonical signaling pathway of SNAI2 induces EMT in ovarian cancer cells by suppressing miR-222-3p transcription and upregulating PDCD10

Background: Epithelial ovarian cancer (EOC) is one of the most lethal malignancies in women worldwide. Many studies showed the transcription factor SNAI2-induced Epithelial-Mesenchymal Transition (EMT) through inhibiting E-cadherin (E-cad) expression. Our previous study reported that miR-222-3p was...

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Detalles Bibliográficos
Autores principales: Fan, Lili, Lei, Han, Zhang, Sai, Peng, Yulong, Fu, Chunyan, Shu, Guang, Yin, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7254989/
https://www.ncbi.nlm.nih.gov/pubmed/32483426
http://dx.doi.org/10.7150/thno.43198