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Design and validation of fibroblast activation protein alpha targeted imaging and therapeutic agents

Background: Cancer-associated fibroblasts (CAFs) comprise a major cell type in the tumor microenvironment where they support tumor growth and survival by producing extracellular matrix, secreting immunosuppressive cytokines, releasing growth factors, and facilitating metastases. Because tumors with...

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Detalles Bibliográficos
Autores principales: Roy, Jyoti, Hettiarachchi, Suraj U, Kaake, Miranda, Mukkamala, Ramesh, Low, Philip S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7254991/
https://www.ncbi.nlm.nih.gov/pubmed/32483418
http://dx.doi.org/10.7150/thno.41409