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Skipping of exon 10 in Axl pre-mRNA regulated by PTBP1 mediates invasion and metastasis process of liver cancer cells

The Axl gene is known to encode for a receptor tyrosine kinase involved in the metastasis process of cancer. In this study, we investigated the underlying molecular mechanism of Axl alternative splicing. Methods: The expression levels of PTBP1 in hepatocellular carcinoma (HCC) tissues were obtained...

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Detalles Bibliográficos
Autores principales: Shen, Lianghua, Lei, Sijia, Zhang, Bin, Li, Shuaiguang, Huang, Luyuan, Czachor, Alexander, Breitzig, Mason, Gao, Yuman, Huang, Meiyan, Mo, Xuemei, Zheng, Qing, Sun, Hanxiao, Wang, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7255001/
https://www.ncbi.nlm.nih.gov/pubmed/32483414
http://dx.doi.org/10.7150/thno.42010