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(89)Zr-PET imaging of DNA double-strand breaks for the early monitoring of response following α- and β-particle radioimmunotherapy in a mouse model of pancreatic ductal adenocarcinoma

Rationale: The evaluation of early treatment response is critical for patient prognosis and treatment planning. When the current methods rely on invasive protocols that evaluate the expression of DNA damage markers on patient biopsy samples, we aim to evaluate a non-invasive PET imaging approach to...

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Detalles Bibliográficos
Autores principales: Poty, Sophie, Mandleywala, Komal, O'Neill, Edward, Knight, James C., Cornelissen, Bart, Lewis, Jason S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7255009/
https://www.ncbi.nlm.nih.gov/pubmed/32483420
http://dx.doi.org/10.7150/thno.44772