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CXCR4 mediates matrix stiffness-induced downregulation of UBTD1 driving hepatocellular carcinoma progression via YAP signaling pathway

Rational: Increasing evidence indicates that the physical environment is a critical mediator of tumor behavior. Hepatocellular carcinoma (HCC) develops in an altered biomechanical environment, and increased matrix stiffness is a strong predictor of HCC development. C-X-C chemokine receptor type 4 (C...

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Detalles Bibliográficos
Autores principales: Yang, Nan, Chen, Tianxiang, Wang, Liang, Liu, Runkun, Niu, Yongshen, Sun, Liankang, Yao, Bowen, Wang, Yufeng, Yang, Wei, Liu, Qingguang, Tu, Kangsheng, Liu, Zhikui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7255012/
https://www.ncbi.nlm.nih.gov/pubmed/32483419
http://dx.doi.org/10.7150/thno.44789