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CXCR4 mediates matrix stiffness-induced downregulation of UBTD1 driving hepatocellular carcinoma progression via YAP signaling pathway
Rational: Increasing evidence indicates that the physical environment is a critical mediator of tumor behavior. Hepatocellular carcinoma (HCC) develops in an altered biomechanical environment, and increased matrix stiffness is a strong predictor of HCC development. C-X-C chemokine receptor type 4 (C...
Autores principales: | Yang, Nan, Chen, Tianxiang, Wang, Liang, Liu, Runkun, Niu, Yongshen, Sun, Liankang, Yao, Bowen, Wang, Yufeng, Yang, Wei, Liu, Qingguang, Tu, Kangsheng, Liu, Zhikui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7255012/ https://www.ncbi.nlm.nih.gov/pubmed/32483419 http://dx.doi.org/10.7150/thno.44789 |
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