Interplay between MycN and c-Myc regulates radioresistance and cancer stem cell phenotype in neuroblastoma upon glutamine deprivation

Targeting glutamine metabolism has emerged as a potential therapeutic strategy for Myc overexpressing cancer cells. Myc proteins contribute to an aggressive neuroblastoma phenotype. Radiotherapy is one of the treatment modalities for high-risk neuroblastoma patients. Herein, we investigated the effe...

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Detalles Bibliográficos
Autores principales: Le Grand, Marion, Mukha, Anna, Püschel, Jakob, Valli, Emanuele, Kamili, Alvin, Vittorio, Orazio, Dubrovska, Anna, Kavallaris, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7255021/
https://www.ncbi.nlm.nih.gov/pubmed/32483461
http://dx.doi.org/10.7150/thno.42602

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7255021/
https://www.ncbi.nlm.nih.gov/pubmed/32483461
http://dx.doi.org/10.7150/thno.42602

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