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Diethyldithiocarbamate-copper nanocomplex reinforces disulfiram chemotherapeutic efficacy through light-triggered nuclear targeting

To circumvent the huge cost, long R&D time and the difficulty to identify the targets of new drugs, repurposing the ones that have been clinically approved has been considered as a viable strategy to treat different diseases. In the current study, we outlined the rationale for repurposing disulf...

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Detalles Bibliográficos
Autores principales: Ren, Liting, Feng, Wenya, Shao, Jie, Ma, Juan, Xu, Ming, Zhu, Ben-Zhan, Zheng, Nanfeng, Liu, Sijin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7255023/
https://www.ncbi.nlm.nih.gov/pubmed/32483459
http://dx.doi.org/10.7150/thno.45558