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HLA class-I and class-II restricted neoantigen loads predict overall survival in breast cancer

Tumors acquire numerous mutations during development and progression. When translated into proteins, these mutations give rise to neoantigens that can be recognized by T cells and generate antibodies, representing an exciting direction of cancer immunotherapy. While neoantigens have been reported in...

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Detalles Bibliográficos
Autores principales: Ren, Yingxue, Cherukuri, Yesesri, Wickland, Daniel P., Sarangi, Vivekananda, Tian, Shulan, Carter, Jodi M., Mansfield, Aaron S., Block, Matthew S., Sherman, Mark E., Knutson, Keith L., Lin, Yi, Asmann, Yan W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7255108/
https://www.ncbi.nlm.nih.gov/pubmed/32523802
http://dx.doi.org/10.1080/2162402X.2020.1744947