Cargando…

HLA class-I and class-II restricted neoantigen loads predict overall survival in breast cancer

Tumors acquire numerous mutations during development and progression. When translated into proteins, these mutations give rise to neoantigens that can be recognized by T cells and generate antibodies, representing an exciting direction of cancer immunotherapy. While neoantigens have been reported in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ren, Yingxue, Cherukuri, Yesesri, Wickland, Daniel P., Sarangi, Vivekananda, Tian, Shulan, Carter, Jodi M., Mansfield, Aaron S., Block, Matthew S., Sherman, Mark E., Knutson, Keith L., Lin, Yi, Asmann, Yan W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7255108/ https://www.ncbi.nlm.nih.gov/pubmed/32523802 http://dx.doi.org/10.1080/2162402X.2020.1744947

Ejemplares similares

Identification of Novel HLA Class II-Restricted Neoantigens Derived from Driver Mutations
por: Iiizumi, Susumu, et al.
Publicado: (2019)

Identification of HLA class I-restricted immunogenic neoantigens in triple negative breast cancer
por: Aparicio, Belén, et al.
Publicado: (2022)

Hepatobiliary Tumor Organoids Reveal HLA Class I Neoantigen Landscape and Antitumoral Activity of Neoantigen Peptide Enhanced with Immune Checkpoint Inhibitors
por: Wang, Wenwen, et al.
Publicado: (2022)

Immunopeptidomics of colorectal cancer organoids reveals a sparse HLA class I neoantigen landscape and no increase in neoantigens with interferon or MEK-inhibitor treatment
por: Newey, Alice, et al.
Publicado: (2019)

Proteogenomic identification of an immunogenic HLA class I neoantigen in mismatch repair–deficient colorectal cancer tissue
por: Hirama, Tomomi, et al.
Publicado: (2021)

Vaccine Strain-Specificity of Protective HLA-Restricted Class 1 P. falciparum Epitopes
por: Sedegah, Martha, et al.
Publicado: (2016)

Structural engineering of chimeric antigen receptors targeting HLA-restricted neoantigens
por: Hwang, Michael S., et al.
Publicado: (2021)

Generation of novel complete HLA class I monoallelic cell lines used in an MHC stabilization assay for neoantigen evaluation
por: Iizuka, Akira, et al.
Publicado: (2023)

Correction: Vaccine Strain-Specificity of Protective HLA-Restricted Class 1 P. falciparum Epitopes
por: Sedegah, Martha, et al.
Publicado: (2016)

Identification of Claudin 6-specific HLA class I- and HLA class II-restricted T cell receptors for cellular immunotherapy in ovarian cancer
por: Matsuzaki, Junko, et al.
Publicado: (2022)

Lower Exome Sequencing Coverage of Ancestrally African Patients in The Cancer Genome Atlas
por: Wickland, Daniel P, et al.
Publicado: (2022)

Targeting Telomerase with an HLA Class II-Restricted TCR for Cancer Immunotherapy
por: Dillard, Pierre, et al.
Publicado: (2021)

HLA class I loss in metachronous metastases prevents continuous T cell recognition of mutated neoantigens in a human melanoma model
por: Schrörs, Barbara, et al.
Publicado: (2017)

Characterization of CD8(+) T-cell responses to non-anchor-type HLA class I neoantigens with single amino-acid substitutions
por: Shinkawa, Tomoyo, et al.
Publicado: (2021)

Neoantigen Vaccines; Clinical Trials, Classes, Indications, Adjuvants and Combinatorial Treatments
por: Niemi, Jenni Viivi Linnea, et al.
Publicado: (2022)

Direct identification of HLA class I and class II-restricted T cell epitopes in pancreatic cancer tissues by mass spectrometry
por: Fujiwara, Kenji, et al.
Publicado: (2022)

HLA Class I Restriction as a Possible Driving Force for Chikungunya Evolution
por: Tong, Joo Chuan, et al.
Publicado: (2010)

Somatic Variation of T-Cell Receptor Genes Strongly Associate with HLA Class Restriction
por: Klarenbeek, Paul L., et al.
Publicado: (2015)

A conjoined universal helper epitope can unveil antitumor effects of a neoantigen vaccine targeting an MHC class I-restricted neoepitope
por: Swartz, Adam M., et al.
Publicado: (2021)

Neoantigen characteristics in the context of the complete predicted MHC class I self-immunopeptidome
por: Brown, Scott D., et al.
Publicado: (2018)

The identification of HLA class II-restricted T cell epitopes to vaccinia virus membrane proteins
por: Kennedy, Richard B., et al.
Publicado: (2010)

Multiple sclerosis: Molecular mimicry of an antimyelin HLA class I restricted T-cell receptor
por: Rühl, Geraldine, et al.
Publicado: (2016)

Immunogenicity of HLA Class I and II Double Restricted Influenza A-Derived Peptides
por: Pedersen, Sara Ram, et al.
Publicado: (2016)

HLA class II-Restricted CD8+ T cells in HIV-1 Virus Controllers
por: Nyanhete, Tinashe E., et al.
Publicado: (2019)

Targeting KRAS mutations with HLA class II-restricted TCRs for the treatment of solid tumors
por: Dillard, Pierre, et al.
Publicado: (2021)

HLA class II transgenic mice: the chance to unravel the basis of HLA class II associations with disease
Publicado: (1994)

Identification of presented SARS-CoV-2 HLA class I and HLA class II peptides using HLA peptidomics
por: Nagler, Adi, et al.
Publicado: (2021)

Benchmarking of de novo assembly algorithms for Nanopore data reveals optimal performance of OLC approaches
por: Cherukuri, Yesesri, et al.
Publicado: (2016)

INeo-Epp: A Novel T-Cell HLA Class-I Immunogenicity or Neoantigenic Epitope Prediction Method Based on Sequence-Related Amino Acid Features
por: Wang, Guangzhi, et al.
Publicado: (2020)

Elevated neoantigen levels in tumors with somatic mutations in the HLA-A, HLA-B, HLA-C and B2M genes
por: Castro, Andrea, et al.
Publicado: (2019)

Identification of HLA-A2-Restricted Mutant Epitopes from Neoantigens of Esophageal Squamous Cell Carcinoma
por: Wang, Zhiwei, et al.
Publicado: (2021)

Cytotoxic T cell recognition of an endogenous class I HLA peptide presented by a class II HLA molecule
Publicado: (1990)

Expression of HLA Class I and HLA Class II by Tumor Cells in Chinese Classical Hodgkin Lymphoma Patients
por: Huang, Xin, et al.
Publicado: (2010)

Apparent lack of MHC restriction in binding of class I HLA molecules to solid-phase peptides
Publicado: (1990)

Cytomegalovirus induces HLA-class-II-restricted alloreactivity in an acute myeloid leukemia cell line
por: Koldehoff, Michael, et al.
Publicado: (2018)

HLA class I-restricted T cell epitopes isolated and identified from myeloid leukemia cells
por: Nyambura, Lydon Wainaina, et al.
Publicado: (2019)

The Association of HLA-Class I and Class II with Hodgkin's Lymphoma in Iranian Patients
por: Sayad, Arezou, et al.
Publicado: (2014)

HLA Class I and Class II Associations with ESRD in Saudi Arabian Population
por: Hamdi, Nuha Mahmoud, et al.
Publicado: (2014)

Influence of HLA class I, HLA class II and KIRs on vertical transmission and chronicity of hepatitis C virus in children
por: Ruiz-Extremera, A., et al.
Publicado: (2017)

HLA class I allele promiscuity revisited
por: Rao, Xiangyu, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_hmvkk61aq6bfj0gsa8i228p0nn