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Overexpression of Platelet-Derived Growth Factor Receptor Α D842V Mutants Prevents Liver Regeneration and Chemically Induced Hepatocarcinogenesis via Inhibition of MET and EGFR

Platelet-derived growth receptor α (PDGFRα) is a key factor in many pathophysiological processes. The expression level of PDGFRα is significantly elevated in the early stage of liver development and maintained at a lower level in adult normal livers. In this study, we constructed a liver-specific PD...

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Detalles Bibliográficos
Autores principales: Du, Zhao-Qing, Dong, Jian, Li, Mu-Xing, Zhang, Jian-Fei, Bi, Jian-Bin, Ren, Yi-Fan, Zhang, Li-Na, Wu, Rong-Qian, Monga, Satdarshan P.S., Lv, Yi, Zhang, Xu-Feng, Wang, Hai-Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7255377/
https://www.ncbi.nlm.nih.gov/pubmed/32489479
http://dx.doi.org/10.7150/jca.44492