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MicroRNA-1 regulates the development of osteoarthritis in a Col2a1-Cre-ER(T2)/GFP(fl/fl)-RFP-miR-1 mouse model of osteoarthritis through the downregulation of Indian hedgehog expression
The present study assessed the effects of microRNA-1 (miR-1) on the development of osteoarthritis using human tissues and a Col2a1-Cre-ER(T2)/GFP(fl/fl)-RFP-miR-1 mouse model of osteoarthritis. Human cartilage tissues (n=20) were collected for reverse transcription-quantitative polymerase chain reac...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7255451/ https://www.ncbi.nlm.nih.gov/pubmed/32626917 http://dx.doi.org/10.3892/ijmm.2020.4601 |