MicroRNA-1 regulates the development of osteoarthritis in a Col2a1-Cre-ER(T2)/GFP(fl/fl)-RFP-miR-1 mouse model of osteoarthritis through the downregulation of Indian hedgehog expression

The present study assessed the effects of microRNA-1 (miR-1) on the development of osteoarthritis using human tissues and a Col2a1-Cre-ER(T2)/GFP(fl/fl)-RFP-miR-1 mouse model of osteoarthritis. Human cartilage tissues (n=20) were collected for reverse transcription-quantitative polymerase chain reac...

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Detalles Bibliográficos
Autores principales: Che, Xianda, Chen, Taoyu, Wei, Lei, Gu, Xiaodong, Gao, Yangyang, Liang, Shufen, Li, Penghua, Shi, Dongping, Liang, Bin, Wang, Chunfang, Li, Pengcui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7255451/
https://www.ncbi.nlm.nih.gov/pubmed/32626917
http://dx.doi.org/10.3892/ijmm.2020.4601

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