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Osteocyte TGFβ1-Smad2/3 is positively associated with bone turnover parameters in subchondral bone of advanced osteoarthritis

Subchondral sclerosis is considered the main characteristic of advanced osteoarthritis, in which bone remodeling mediated by transforming growth factor β (TGFβ) signaling plays an indispensable role in the metabolism. Osteocytes have been identified as pivotal regulators of bone metabolism, due to t...

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Detalles Bibliográficos
Autores principales: Dai, Guangming, Xiao, Haozhuo, Liao, Junyi, Zhou, Nian, Zhao, Chen, Xu, Wei, Xu, Wenjuan, Liang, Xi, Huang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7255453/
https://www.ncbi.nlm.nih.gov/pubmed/32319543
http://dx.doi.org/10.3892/ijmm.2020.4576