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Emerging roles of let-7d in attenuating pulmonary arterial hypertension via suppression of pulmonary artery endothelial cell autophagy and endothelin synthesis through ATG16L1 downregulation

Pulmonary arterial hypertension (PAH) is a severe disease characterized by elevated pulmonary arterial pressure and pulmonary vascular resistance, resulting in right ventricular failure and death. Compelling evidence has suggested the roles of microRNAs (miRNAs/miRs) in PAH. The present study invest...

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Detalles Bibliográficos
Autores principales: Ou, Minghui, Li, Xia, Cui, Shichao, Zhao, Shibo, Tu, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7255485/
https://www.ncbi.nlm.nih.gov/pubmed/32319531
http://dx.doi.org/10.3892/ijmm.2020.4567