An osteocalcin-deficient mouse strain without endocrine abnormalities

Osteocalcin (OCN), the most abundant noncollagenous protein in the bone matrix, is reported to be a bone-derived endocrine hormone with wide-ranging effects on many aspects of physiology, including glucose metabolism and male fertility. Many of these observations were made using an OCN-deficient mou...

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Detalles Bibliográficos
Autores principales: Diegel, Cassandra R., Hann, Steven, Ayturk, Ugur M., Hu, Jennifer C. W., Lim, Kyung-eun, Droscha, Casey J., Madaj, Zachary B., Foxa, Gabrielle E., Izaguirre, Isaac, Transgenics Core, VAI Vivarium and, Paracha, Noorulain, Pidhaynyy, Bohdan, Dowd, Terry L., Robling, Alexander G., Warman, Matthew L., Williams, Bart O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7255615/
https://www.ncbi.nlm.nih.gov/pubmed/32463812
http://dx.doi.org/10.1371/journal.pgen.1008361