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An osteocalcin-deficient mouse strain without endocrine abnormalities
Osteocalcin (OCN), the most abundant noncollagenous protein in the bone matrix, is reported to be a bone-derived endocrine hormone with wide-ranging effects on many aspects of physiology, including glucose metabolism and male fertility. Many of these observations were made using an OCN-deficient mou...
Autores principales: | Diegel, Cassandra R., Hann, Steven, Ayturk, Ugur M., Hu, Jennifer C. W., Lim, Kyung-eun, Droscha, Casey J., Madaj, Zachary B., Foxa, Gabrielle E., Izaguirre, Isaac, Transgenics Core, VAI Vivarium and, Paracha, Noorulain, Pidhaynyy, Bohdan, Dowd, Terry L., Robling, Alexander G., Warman, Matthew L., Williams, Bart O. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7255615/ https://www.ncbi.nlm.nih.gov/pubmed/32463812 http://dx.doi.org/10.1371/journal.pgen.1008361 |
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