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Coordination of Rheb lysosomal membrane interactions with mTORC1 activation
A complex molecular machinery converges on the surface of lysosomes to ensure that the growth-promoting signaling mediated by mechanistic target of rapamycin complex 1 (mTORC1) is tightly controlled by the availability of nutrients and growth factors. The final step in this activation process is dep...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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F1000 Research Limited
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7255682/ https://www.ncbi.nlm.nih.gov/pubmed/32518628 http://dx.doi.org/10.12688/f1000research.22367.1 |