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crispRdesignR: A Versatile Guide RNA Design Package in R for CRISPR/Cas9 Applications

The success of CRISPR/Cas9 gene editing applications relies on the efficiency of the single guide RNA (sgRNA) used in conjunction with the Cas9 protein. Current sgRNA design software vary in the details they provide on sgRNA sequence efficiency and usually limit organism choice to a list of develope...

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Detalles Bibliográficos
Autores principales: Beeber, Dylan, Chain, Frédéric JJ
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7256011/
https://www.ncbi.nlm.nih.gov/pubmed/32494309
http://dx.doi.org/10.7150/jgen.41196