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TGFβ-induced metabolic reprogramming during epithelial-to-mesenchymal transition in cancer

Metastasis is the most frequent cause of death in cancer patients. Epithelial-to-mesenchymal transition (EMT) is the process in which cells lose epithelial integrity and become motile, a critical step for cancer cell invasion, drug resistance and immune evasion. The transforming growth factor-β (TGF...

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Detalles Bibliográficos
Autores principales: Hua, Wan, ten Dijke, Peter, Kostidis, Sarantos, Giera, Martin, Hornsveld, Marten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7256023/
https://www.ncbi.nlm.nih.gov/pubmed/31822964
http://dx.doi.org/10.1007/s00018-019-03398-6