Synergistic antifibrotic effects of miR-451 with miR-185 partly by co-targeting EphB2 on hepatic stellate cells

Liver fibrosis is a global health problem currently without clinically approved drugs. It is characterized by the excessive accumulation of extracellular matrix (ECM) mainly produced by activated hepatic stellate cells (HSCs). Uncovering the mechanisms underlying the fibrogenic responses in HSCs may...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Xiaogang, Zhang, Dan, Wang, Yi, Chen, Ke, Zhao, Limeng, Xu, Yating, Jiang, Hulin, Wang, Shuzhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7256034/
https://www.ncbi.nlm.nih.gov/pubmed/32467578
http://dx.doi.org/10.1038/s41419-020-2613-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7256034/
https://www.ncbi.nlm.nih.gov/pubmed/32467578
http://dx.doi.org/10.1038/s41419-020-2613-y

Ejemplares similares