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Synergistic antifibrotic effects of miR-451 with miR-185 partly by co-targeting EphB2 on hepatic stellate cells
Liver fibrosis is a global health problem currently without clinically approved drugs. It is characterized by the excessive accumulation of extracellular matrix (ECM) mainly produced by activated hepatic stellate cells (HSCs). Uncovering the mechanisms underlying the fibrogenic responses in HSCs may...
Autores principales: | Chen, Xiaogang, Zhang, Dan, Wang, Yi, Chen, Ke, Zhao, Limeng, Xu, Yating, Jiang, Hulin, Wang, Shuzhen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7256034/ https://www.ncbi.nlm.nih.gov/pubmed/32467578 http://dx.doi.org/10.1038/s41419-020-2613-y |
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