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Nephroprotective activity of virgin coconut oil on diclofenac-induced oxidative nephrotoxicity is associated with antioxidant and anti-inflammatory effects in rats

OBJECTIVE: Diclofenac is a non-steroidal anti-inflammatory drug linked with considerable organ toxicity caused via increased generation of reactive oxygen species. We evaluated whether the antioxidant effect of virgin coconut oil (VCO) could prevent diclofenac-induced oxidative nephrotoxicity in rat...

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Detalles Bibliográficos
Autores principales: Famurewa, Ademola C, Akunna, Gabriel G, Nwafor, Joseph, Chukwu, Onyebuchi C, Ekeleme-Egedigwe, Chima A, Oluniran, Janet N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7256280/
https://www.ncbi.nlm.nih.gov/pubmed/32523886