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Targeted Myoglobin Delivery as a Strategy for Enhancing the Sensitivity of Hypoxic Cancer Cells to Radiation

The effectiveness of cancer radiotherapy is frequently hindered by the hypoxia of the tumor microenvironment. Direct delivery of oxygen to hypoxic tumor tissues is an attractive strategy to overcome this hypoxia-associated radioresistance. Herein, we report the generation of submicron-sized particle...

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Detalles Bibliográficos
Autores principales: Yang, Zaofeng, Heater, Bradley S., Cuddington, Clayton T., Palmer, Andre F., Lee, Marianne M.M., Chan, Michael K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7256644/
https://www.ncbi.nlm.nih.gov/pubmed/32464594
http://dx.doi.org/10.1016/j.isci.2020.101158