Per2 attenuates LPS-induced chondrocyte injury through the PTEN/PI3K/Akt signalling pathway

This research aimed to explore the role of period circadian clock 2 (Per2) in the evolution of osteoarthritis (OA) and the relevant mechanisms. Per2 messenger RNA (mRNA) and protein levels were markedly reduced in NHAC-kn cells treated with 5 µg/ml lipopolysaccharide (LPS) for 12 h. Then, pcDNA3.1-P...

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Detalles Bibliográficos
Autores principales: Zhao, Yu, Ma, Ding, Dong, Bingchen, Li, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Cell Death & Injury
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7256672/
https://www.ncbi.nlm.nih.gov/pubmed/32426819
http://dx.doi.org/10.1042/BSR20200417

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7256672/
https://www.ncbi.nlm.nih.gov/pubmed/32426819
http://dx.doi.org/10.1042/BSR20200417

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